Ensemble based Model for Diabetes Prediction and COVID-19 Mortality Risk Assessment in Diabetic Patients
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Abstract
Millions of individuals worldwide suffer from a chronic ailment known as diabetes, which can harm several organs, including the kidneys, eyes, and heart arteries. Diabetes patients are those who are most impacted by COVID-19. This study explores machine learning techniques for predicting diabetes and assessing COVID-19 mortality risks for diabetic patients. The study was conducted on diabetes and covid 19 datasets containing patients' demographic and clinical features. The machine learning techniques Support Vector Machine, Random Forest, Multilayer Perceptron, Naive Bayes, and Logistic Regression are used on both datasets. Additionally, their combination is employed to improve the performances of the models. These algorithms' accuracy, precision, recall, and F1-score were evaluated to determine their performance in predicting diabetes and COVID-19. By making this enhancement, healthcare services could use less time, labor, and resources while also making decisions with more reliability. The study results showed that the ensemble model had the highest accuracy in predicting diabetes and covid 19. The study also found that older age, higher HbA1c levels, and comorbidities significantly predict mortality risk in diabetic patients with COVID-19. The study concludes that machine learning techniques can help predict diabetes and assess COVID-19 mortality risks in diabetic patients. These findings could aid in developing effective prevention and treatment strategies for diabetes and COVID-19.
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References
T. Beghriche, M. Djerioui, Y. Brik, B. Attallah, and S. B. Belhaouari, “An Efficient Prediction System for Diabetes Disease Based on Deep Neural Network,” Complexity, vol. 2021, 2021, doi: 10.1155/2021/6053824.
U. M. Butt, S. Letchmunan, M. Ali, F. H. Hassan, A. Baqir, and H. H. R. Sherazi, “Machine Learning Based Diabetes Classification and Prediction for Healthcare Applications,” J Healthc Eng, vol. 2021, 2021, doi: 10.1155/2021/9930985.
M. M. Bukhari, B. F. Alkhamees, S. Hussain, A. Gumaei, A. Assiri, and S. S. Ullah, “An Improved Artificial Neural Network Model for Effective Diabetes Prediction,” Complexity, vol. 2021, 2021, doi: 10.1155/2021/5525271.
P. Rajendra and S. Latifi, “Prediction of diabetes using logistic regression and ensemble techniques,” Computer Methods and Programs in Biomedicine Update, vol. 1, p. 100032, 2021, doi: 10.1016/j.cmpbup.2021.100032.
L. Roncon, M. Zuin, G. Rigatelli, and G. Zuliani, “Diabetic patients with COVID-19 infection are at higher risk of ICU admission and poor short-term outcome,” J Clin Virol, vol. 127, Jun. 2020, doi: 10.1016/J.JCV.2020.104354.
H. Khadem, H. Nemat, M. R. Eissa, J. Elliott, and M. Benaissa, “COVID-19 mortality risk assessments for individuals with and without diabetes mellitus: Machine learning models integrated with interpretation framework,” Comput Biol Med, vol. 144, May 2022, doi: 10.1016/J.COMPBIOMED.2022.105361.
G. Li, Q. Deng, J. Feng, F. Li, N. Xiong, and Q. He, “Clinical Characteristics of Diabetic Patients with COVID-19,” J Diabetes Res, vol. 2020, 2020, doi: 10.1155/2020/1652403.
C. Huang et al., “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China,” The Lancet, vol. 395, no. 10223, pp. 497–506, Feb. 2020, doi: 10.1016/S0140-6736(20)30183-5.
J. jin Zhang et al., “Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China,” Allergy, vol. 75, no. 7, pp. 1730–1741, Jul. 2020, doi: 10.1111/ALL.14238.
J. Wu et al., “Influence of diabetes mellitus on the severity and fatality of SARS-CoV-2 (COVID-19) infection,” Diabetes Obes Metab, vol. 22, no. 10, pp. 1907–1914, Oct. 2020, doi: 10.1111/DOM.14105.
X. W. Xu et al., “Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case series,” BMJ, vol. 368, Feb. 2020, doi: 10.1136/BMJ.M606.
G. P. Fadini, M. L. Morieri, E. Longato, and A. Avogaro, “Prevalence and impact of diabetes among people infected with SARS-CoV-2,” J Endocrinol Invest, vol. 43, no. 6, pp. 867–869, Jun. 2020, doi: 10.1007/S40618-020-01236-2.
S. Richardson et al., “Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area,” JAMA, vol. 323, no. 20, pp. 2052–2059, May 2020, doi: 10.1001/JAMA.2020.6775.
M. R. Mehra, S. S. Desai, S. Kuy, T. D. Henry, and A. N. Patel, “Cardiovascular Disease, Drug Therapy, and Mortality in Covid-19,” N Engl J Med, vol. 382, no. 25, p. e102, Jun. 2020, doi: 10.1056/NEJMOA2007621.
I. Huang, M. A. Lim, and R. Pranata, “Diabetes mellitus is associated with increased mortality and severity of disease in COVID-19 pneumonia – A systematic review, meta-analysis, and meta-regression,” Diabetes & Metabolic Syndrome: Clinical Research & Reviews, vol. 14, no. 4, pp. 395–403, Jul. 2020, doi: 10.1016/J.DSX.2020.04.018.
L. Zhu et al., “Association of Blood Glucose Control and Outcomes in Patients with COVID-19 and Pre-existing Type 2 Diabetes,” Cell Metab, vol. 31, no. 6, pp. 1068-1077.e3, Jun. 2020, doi: 10.1016/J.CMET.2020.04.021.
G. P. Fadini et al., “Newly-diagnosed diabetes and admission hyperglycemia predict COVID-19 severity by aggravating respiratory deterioration,” Diabetes Res Clin Pract, vol. 168, Oct. 2020, doi: 10.1016/J.DIABRES.2020.108374.
Y. Mahamat-Saleh et al., “Diabetes, hypertension, body mass index, smoking and COVID-19-related mortality: a systematic review and meta-analysis of observational studies,” BMJ Open, vol. 11, no. 10, Oct. 2021, doi: 10.1136/BMJOPEN-2021-052777.
S. Jaiswal and P. Gupta, “MLP-DTP: Performance Evaluation of Diabetes Class Prediction,” IEMECON 2021 - 10th International Conference on Internet of Everything, Microwave Engineering, Communication and Networks, 2021, doi: 10.1109/IEMECON53809.2021.9689183.
H. T. Abbas et al., “Predicting long-term type 2 diabetes with support vector machine using oral glucose tolerance test,” PLoS One, vol. 14, no. 12, Dec. 2019, doi: 10.1371/JOURNAL.PONE.0219636.
K. Vijiyakumar, B. Lavanya, I. Nirmala, and S. Sofia Caroline, “Random Forest Algorithm for the Prediction of Diabetes,” undefined, Mar. 2019, doi: 10.1109/ICSCAN.2019.8878802.
M. Alehegn, R. Joshi, and P. Mulay, “Diabetes Analysis And Prediction Using Random Forest, KNN, Naïve Bayes, And J48: An Ensemble Approach,” undefined, 2019.
H. Salem, M. Y. Shams, O. M. Elzeki, M. A. Elfattah, J. F. Al‐amri, and S. Elnazer, “Fine-Tuning Fuzzy KNN Classifier Based on Uncertainty Membership for the Medical Diagnosis of Diabetes,” Applied Sciences 2022, Vol. 12, Page 950, vol. 12, no. 3, p. 950, Jan. 2022, doi: 10.3390/APP12030950.
S. Islam Ayon and Md. Milon Islam, “Diabetes Prediction: A Deep Learning Approach,” International Journal of Information Engineering and Electronic Business, vol. 11, no. 2, pp. 21–27, Mar. 2019, doi: 10.5815/IJIEEB.2019.02.03.
A. K. Dwivedi, “Analysis of computational intelligence techniques for diabetes mellitus prediction,” Neural Comput Appl, vol. 30, no. 12, pp. 3837–3845, Dec. 2018, doi: 10.1007/S00521-017-2969-9/FIGURES/7.