International Journal of Computer Engineering in Research Trends

Back to Current Issues

A Review: Molecular Imaging Techniques to Monitor NK Cells in Vivo in a Preclinical and Clinical Scenario

Yi-Chia Lee, Ming-Yii Huang, , ,

Affiliations
Kaohsiung Medical University, Canter for Cancer Research

:10.22362/ijcert/2019/v6/i08/v6i0802

Abstract

In recent years, the use of natural killer (NK) -based immunotherapy has shown promising measures against various cancers. The therapeutic efficacy of NK cell immunotherapy depends to some extent on the migration of NK cells and subsequent infiltration into tumours in animal models or in humans. The continuous improvement of the healing and therapeutic properties of NK cells stimulates the performance and use of immunotherapy based on NK cells. In this review, we summarize the molecular imaging techniques used to monitor NK cell migration and infiltration in vivo, both preclinical and clinically. The advantages and disadvantages of each molecular imaging modality are considered. Finally, we present our understanding of the use of molecular imaging techniques to monitor NK cells in vivo in a preclinical and clinical scenario.

Citation

Yi-Chia Lee, Ming-Yii Huang."A Review: Molecular Imaging Techniques to Monitor NK Cells in Vivo in a Preclinical and Clinical Scenario". International Journal of Computer Engineering In Research Trends (IJCERT) , ISSN:2349-7084,Vol.6, Issue 08,pp.7-14,August - 2019,https://ijcert.org/ems/ijcert_papers/V6I802.pdf

Keywords : photoacoustic imaging; optoacoustic imaging; breast imaging; breast cancer detection; breast phantom imaging; animal breast imaging; in vivo breast imaging; breast cancer screening; breast cancer diagnosis, bioluminescent; RI; SPECT; PET

References

1. Siegel, R.L.; Miller, K.D.; Jemal, A. Cancer statistics, 2017. CA Cancer J. Clin. 2017, 67, 7–30. [CrossRef] [PubMed]
2. Hugosson, J.; Carlsson, S. Overdetection in screening for prostate cancer. Curr. Opin. Urol. 2014, 24, 256–263. [CrossRef] [PubMed]
3. Schröder, F.H.; Hugosson, J.; Roobol, M.J.; Tammela, T.L.; Ciatto, S.; Nelen, V.; Kwiatkowski, M.; Lujan, M.; Lilja, H.; Zappa, M.; et al. Screening and prostate-cancer mortality in a randomized European study. N. Engl. J. Med. 2009, 360, 1320–1328. [CrossRef] [PubMed]
4. Oberlin, D.T.; Casalino, D.D.; Miller, F.H.; Meeks, J.J. Dramatic increase in the utilization of multiparametric magnetic resonance imaging for detection and management of prostate cancer. Abdom. Radiol. (Ny) 2017, 42, 1255–1258. [CrossRef] [PubMed]
5. Monni, F.; Fontanella, P.; Grasso, A.;Wiklund, P.; Ou, Y.C.; Randazzo, M.; Rocco, B.; Montanari, E.; Bianchi, G.Magnetic resonance imaging in prostate cancer detection and management: A systematic review. Minerva. Urol. Nefrol. 2017, 69, 567–578. [CrossRef] [PubMed]
6. Vitale, M.; Cantoni, C.; Pietra, G.; Mingari, M.C.; Moretta, L. Effect of tumour cells and tumour microenvironment on NK-cell function. Eur. J. Immunol. 2014, 44, 1582–1592. [CrossRef]
7. Vanherberghen, B.; Olofsson, P.E.; Forslund, E.; Sternberg-Simon, M.; Khorshidi, M.A.; Pacouret, S.; Guldevall, K.; Enqvist, M.; Malmberg, K.-J.; Mehr, R.; et al. Classification of human natural killer cells based on migration behaviour and cytotoxic response. Blood 2013, 121, 1326–1334. [CrossRef]
8. Gong, J.H.; Maki, G.; Klingemann, H.G. Characterization of a human cell line (NK-92) with phenotypical and functional characteristics of activated natural killer cells. Leukemia 1994, 8, 652–658. 
9. Dahlberg, C.I.M.; Sarhan, D.; Chrobok, M.; Duru, A.D.; Alici, E. Natural Killer Cell-Based Therapies Targeting Cancer: Possible Strategies to Gain and Sustain Anti-Tumor Activity. Front. Immunol. 2015, 6. [CrossRef]
10. Rezvani, K.; Rouce, R.H. The Application of Natural Killer Cell Immunotherapy for the Treatment of Cancer. Front. Immunol. 2015, 6. [CrossRef]
11. Garrod, K.R.; Wei, S.H.; Parker, I.; Cahalan, M.D. Natural killer cells actively patrol peripheral lymph nodes forming stable conjugates to eliminate MHC-mismatched targets. Proc. Natl. Acad. Sci. USA 2007, 104, 12081–12086. [CrossRef]
12. Fang, F.; Xiao, W.; Tian, Z. NK cell-based immunotherapy for cancer. Semin. Immunol. 2017. [CrossRef] [PubMed]
13. Lee, B.J.; Mace, E.M. Acquisition of cell migration defines NK cell differentiation from hematopoietic stem cell precursors. bioRxiv 2017, 142380. [CrossRef]
14. Somersalo, K.; Saksela, E. Fibronectin facilitates the migration of human natural killer cells. Eur. J. Immunol.1991, 21, 35–42. [CrossRef]
15. Taub, D.D.; Sayers, T.J.; Carter, C.R.; Ortaldo, J.R. Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis. J. Immunol. 1995, 155, 3877–3888

DOI Link : https://doi.org/10.22362/ijcert/2019/v6/i08/v6i0802

Download :

V6I802.pdf

Refbacks : Currently there are no Refbacks

Announcements

Authors are not required to pay any article-processing charges (APC) for their article to be published open access in Journal IJCERT. No charge is involved in any stage of the publication process, from administrating peer review to copy editing and hosting the final article on dedicated servers. This is free for all authors.

News & Events

Latest issue :Volume 10 Issue 1 Articles In press

A plagiarism check will be implemented for all the articles using world-renowned software. Turnitin.

Digital Object Identifier will be assigned for all the articles being published in the Journal from September 2016 issue, i.e. Volume 3, Issue 9, 2016.

IJCERT is a member of the prestigious.Each of the IJCERT articles has its unique DOI reference.
DOI Prefix : 10.22362/ijcert

IJCERT is member of The Publishers International Linking Association, Inc. (“PILA”)

Emerging Sources Citation Index (in process)

IJCERT title is under evaluation by Scopus.

Key Dates

☞ INVITING SUBMISSIONS FOR THE NEXT ISSUE :

☞ LAST DATE OF SUBMISSION : 31st March 2023

☞ SUBMISSION TO FIRST DECISION : In 7 Days

☞ FINAL DECISION : IN 3 WEEKS FROM THE DAY OF SUBMISSION

Important Announcements

All the authors, conference coordinators, conveners, and guest editors kindly check their articles' originality before submitting them to IJCERT. If any material is found to be duplicate submission or sent to other journals when the content is in the process with IJCERT, fabricated data, cut and paste (plagiarized), at any stage of processing of material, IJCERT is bound to take the following actions.
1. Rejection of the article.
2. The author will be blocked for future communication with IJCERT if duplicate articles are submitted.
3. A letter regarding this will be posted to the Principal/Director of the Institution where the study was conducted.
4. A List of blacklisted authors will be shared among the Chief Editors of other prestigious Journals
We have been screening articles for plagiarism with a world-renowned tool: Turnitin However, it is only rejected if found plagiarized. This more stern action is being taken because of the illegal behavior of a handful of authors who have been involved in ethical misconduct. The Screening and making a decision on such articles costs colossal time and resources for the journal. It directly delays the process of genuine materials.

Citation Index

Citations Indices	All
Citations	1026
h-index	14
i10-index	20
Source: Google Scholar

Acceptance Rate (By Year)

Acceptance Rate (By Year)
Year	Rate
2021	10.8%
2020	13.6%
2019	15.9%
2018	14.5%
2017	16.6%
2016	15.8%
2015	18.2%
2014	20.6%

 Conference Proposal

 Peer Review

 Digital Library

 Register here

 Conference Proposal

 Special Issue Proposal

 Conference Proposal Guidelines

 Upcoming Conference

DOI:10.22362/ijcert

Welcome to IJCERT